Dr. LI Fuli

Professor, Group leader


Dr LI Fuli is now the Microbial Resources group leader at Qingdao institute of Bioenergy and Bioprocess Technology , Chinese Academy of Sciences. Dr. LI received his Bachelor's degree from Lanzhou University in July, 1998, and then he moved to Shandong University where he did his Ph.D. work on metabolic pathway of dibenzothiophene desulfurization in Mycobacterium goodii X7B. From Sep. 2005 to Sep. 2007, he worked in Max Planck Institute of Terrestrial Microbiology at Marburg with Professor Thauer, where he and coworkers successfully found that Re-citrate synthase in Clostridium kluyveri is phylogenetically related to homocitrate synthase and isopropylmalate synthase rather than to Si-citrate synthase, and coupled ferredoxin and crotonoyl-CoA reduction are catalyzed by butyryl-CoA dehydrogenase/ETF complex in Clostridium kluyveri. He and his coworkers have published more than 50 peer-reviewed papers. He is the council member of Shandong Society for Microbiology and committee member of International Affairs Committee of Chinese Society for Microbiology.


Yuan, B., S. A. Wang*, L. Li. 2013. Expression of exoinulinase genes in Saccharomyces cerevisiae to improve ethanol production from inulin sources. Biotechnol Lett (In revision)

Yuan, B., S. A. Wang*, L. Li*. 2013. Improved ethanol fermentation by heterologous endoinulinase and inherent invertase from inulin by Saccharomyces cerevisiae. Bioresour Technol (In press)

Ying, Y., D. D. Meng, X. H. Chen, F. L. Li*. 2013. An extremely thermophilic anaerobic bacterium Caldicellulosiruptor sp. F32 shows distinct properties in the hydrolysis of xylan. Enzyme Microb Tech (doi:10.1016/j.enzmictec.2013.04.004)

Tan, Y., J. J. Liu, Z. Liu, F. L. Li*. 2013. Characterization of two novel butanol dehydrogenases involved in butanol degradation in syngas-utilizing bacterium Clostridium ljungdahlii DSM 13528. J Basic Microbiol (In press)

Liu, J. J., Y. Tan, X. H. Yang, X. H. Chen, F. L. Li*. 2013. Evaluation of reference genes in Clostridium ljungdahlii DSM 13528 for gene expression studies by qRT-PCR. J Biosci Bioeng (doi:10.1016/j.jbiosc.2013.04.011)

Hu, G. R., Y. Fan, L. Zhang, C. Yuan, J. F. Wang, W. J. Li, Q. Hu, F. L. Li*. 2013. Enhanced lipid productivity and photosynthesis efficiency in a Desmodesmus sp. mutant induced by heavy carbon ions. Plos One 8(4):e60700 (doi:10.1371/journal.pone.0060700)

Hu, G. R., S. Q. Ji, Y. C. Yu, S. A. Wang, F. L. Li. 2013. Organisms for biofuels production: natural bioresources and methodologies for improving their biosynthetic potentials. Adv Biochem Engin/Biotechnol(Invited review)

Yuan, C., Y. L. Zheng, P. L. Qi, H. He, W. L. Zhang, J. H. Liu, G.R. Hu, F. L. Li*.2013. Biodiesel from Microalgae: lipid productivity and fatty acid profiles of 53 microalgal strains isolated from East China. Renewable Energy (accepted)

Wang, S. A., F. L. Li*.2013. Invertase SUC2 is the key hydrolase for inulin degradation in Saccharomyces cerevisiae. Appl Environ Microbiol 79(1):403-406

Mao, X. Z, Wang, S., Kan, F. F., Wei, D. Z.*, Li, F. L.*. (2012). A novel dextran dextrinase from Gluconobacter oxydans DSM-2003: Purification and properties. Appl Biochem Biotechnol 168(5):1256-1264. (doi: 10.1007/s12010-012-9854-x.). PMID: 22961394

Ji, S., Wang, S., Tan, Y., Chen, X., Schwarz, W. & Li, F.L.(2012).An untapped bacterial cellulolytic community enriched from coastal marine sediment under anaerobic and thermophilic conditions.FEMS Microbiol Lett,335(1), 39-46.(doi:10.1111/j.1574-6968). PMID: 22788522

Zhang, W. L., Z. Y. Liu, Z. Liu, F. L. Li*. 2012. Butanol production from corncob residue using Clostridium beijerinckii NCIMB 8052. Lett Appl Microbiol (doi: 10.1111/j.1472-765X.2012.03283.x).PMID: 22738279

Hu, N., , B. Yuan, J. Sun*, S. A. Wang*, F. L. Li. 2012. Thermotolerant Kluyveromyces marxianus and Saccharomyces cerevisiae strains representing potentials for bioethanol production from Jerusalem artichoke by consolidated bioprocessing. Appl Microbiol Biotechol (2012, DOI: 10.1007/s00253-012-4240-8). PMID: 22760784

Yuan, B., N. Hu, J. Sun*, S. A. Wang*, F. L. Li. 2012. Purification and characterization of a novel extracellular inulinase from a new yeast species Candida kutaonensis sp. nov. KRF1T. Appl Microbiol Biotechol (DOI: 10.1007/s00253-012-4108-y). PMID: 22622836

Liu, J. H., C. Yuan, G. R. Hu, F. L. Li*. 2012. Effects of light intensity on the growth and lipid accumulation of microalga Scenedesmus sp. 11-1 under nitrogen limitation. Appl Biochem Biotechnol 166(8):2127-2137 (DOI: 10.1007/s12010-012-9639-2). PMID: 22415786

Yuan, C., J. H. Liu, Y. Fan, X. H. Ren, G. R. Hu, F. L. Li*. 2011. Mychonastes afer HSO-3-1 as a potential new source of biodiesel. Biotechnol for Biofuel 4:47. (DOI:10.1186/1754-6834-4-47 ) PMID: 22040677

Wang, S., X. Z. Mao, F. L. Li*. 2011. Characterization of a novel dextran produced by Gluconobacter oxydans DSM 2003. Appl Microbiol Biotechnol 91(2):287-294. (DOI 10.1007/s00253-011-3267-6 ) PMID: 21499762

Zhang, K.D., F. L. Li*. 2011. Isolation and characterization of a chromium-resistant bacterium Serratia sp. Cr-10 from a chromate–contaminated site. Appl Microbiol Biotechnol 90(3):1163-1169.(DOI: 10.1007/s00253-011-3120-y) PMID: 21318365

Liu ZY., Ying Y. , Li FL, Ma CQ. , Xu P . 2010. Butanol production by Clostridium beijerinckii ATCC 55025 from wheat bran. J Ind Microbiol Biotechnol, 37(5): 495-501 (DOI: 10.1007/s10295-010-0695-8) PMID: 20393827

Wang SA., Li FL, Bai FY . 2010. Candida laoshanensis sp. nov. and Candida qingdaoensis sp. nov., two novel anamorphic, ascomycetous yeast species isolated from decayed wood. Int J Syst Evol Microbiol, 60(7): 1697-1701 (DOI 10.1099/ijs.0.015230-0) PMID: 19684309

李福利. 2009. 微生物代谢工程在环保领域的发展趋势,P123-131, 工业生物技术发展报告,中科院生命科学与生物技术局编著, 科学出版社, 北京

Xu P, Feng JH., Yu B, Li FL, Ma CQ . 2009. Recent Developments to Biodesulfurization of Fossil Fuels. Adv Biochem Engin/Biotechnol, 113:255-274 PMID: 19475378

Seedorf, H., W. F. Fricke, B. Veith, H. Brüggemann, H. Liesegang, A. Strittmatter, M. Miethke, W. Buckel, J. Hinderberger, Li FL, C. Hagemeier, R. K. Thauer, and G. Gottschalk. 2008 The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features. Proc. Natl. Acad. Sci. U S A. 105:2128-2133. PMID: 18218779

.Li FL. §, H. Hinderberger§, H. Seedorf, J. Zhang, W. Buckel, and R. K. Thauer. 2008. Coupled ferredoxin- and crotonyl-CoA reduction with NADH catalyzed by the butyryl-CoA dehydrogenase/Etf complex from Clostridium kluyveri. J. Bacteriol. 190:843-850. (§, contribute equally). PMID: 17993531

.Li FL., C. H. Hagemeier, H. Seedor, G. Gottschalk, and R. K. Thauer. 2007. Re-citrate synthase from Clostridium kluyveri is phylogenetically related to homocitrate synthase and isopropylmalate synthase rather than to Si-citrate synthase. J. Bacteriol. 189:4299-4304.PMID: 17400742

.Li FL., Zhang Z, Feng J, Cai X , and Xu P. 2007. Biodesulfurization of DBT in tetradecane and crude oil by a facultative thermophilic bacterium Mycobacterium goodii X7B. J. Biotechnol. 127:222-228. PMID: 16905217

Xu P, Yu B , Li FL, Cai XF , and Ma CQ . 2006. Microbial degradation of sulfur, nitrogen and oxygen heterocycles. Trends in Microbiology 14:398-405. PMID: 16860985

Li FL., Xu P , Feng JH , Meng L, Zheng Y, Luo LL , and Ma CQ . 2005. Microbial desulfurization of gasoline in a Mycobacterium goodii X7B immobilized-cell system. Appl Environ Microbiol 71:276-281.PMID: PMC544250

Li FL., Xu P, Ma CQ, Luo LL, and Wang XS . 2003. Deep desulfurization of hydrodesulfurization-treated diesel oil by a facultative thermophilic bacterium Mycobacterium sp. X7B. FEMS Microbiol. Lett. 223:301-307.